Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.59 |
| ▸ | ACHE | P22303 | 4/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | ODC1 | P11926 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345206 | 0.86 | MKNK2 (0.77) | ELANEACHEMKNK2PTGS2ALOX5 | |
| SCHEMBL2345199 | 0.86 | MKNK2 (0.77) | ELANEACHEMKNK2PTGS2ALOX5 | |
| SCHEMBL8471171 | 0.86 | MKNK2 (0.77) | ELANEACHEMKNK2PTGS2ALOX5 | |
| SCHEMBL5513744 | 0.80 | ABCG2 (0.66) | ELANEACHEMKNK2PTGS2ALOX5 | |
| SCHEMBL5513740 | 0.80 | ABCG2 (0.66) | ELANEACHEMKNK2PTGS2ALOX5 | |
| SCHEMBL16894660 | 0.78 | ODC1 (0.50) | ODC1ABCG2CYP19A1PTPN1 | |
| SCHEMBL909991 | 0.76 | ELANE (0.75) | ELANEACHEPTGS2ALOX5ABCG2 | |
| SCHEMBL3238481 | 0.76 | ELANE (0.74) | ELANEACHEPTGS2ALOX5ABCG2 | |
| SCHEMBL3231721 | 0.75 | ABCG2 (0.78) | ELANEACHEPTGS2ALOX5ABCG2 | |
| SCHEMBL24075552 | 0.74 | ELANE (1.00) | ELANEACHEPTGS2ALOX5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045247-B1 | Compounds for the inhibition of histone deacetylase | NATUREWISE BIOTECH & MEDICALS CORP (TW) | 2015-04-08 | — | — | EP | disclosed |
| US-8008344-B2 | Compounds for the inhibition of histone deacetylase | NatureWise Biotech and Medicals Corporation (TW) | 2011-08-30 | — | — | US | disclosed |
| EP-2045247-A1 | Compounds for the inhibition of histone deacetylase | NatureWise Biotech & Medicals Corporation (TW) | 2009-04-08 | — | — | EP | disclosed |
| US-20090076130-A1 | COMPOUNDS FOR THE INHIBITION OF HISTONE DEACETYLASE | NATUREWISE BIOTECH & MEDICALS CORPORATION (TW) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076130-A1 | COMPOUNDS FOR THE INHIBITION OF HISTONE DEACETYLASE | SMN1; SMN2, HDAC1, HDAC5 | ELANE 1578/4885ACHE 913/4885MKNK2 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.