Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 1.00 |
| ▸ | ACHE | P22303 | 6/20 | 0.87 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.84 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.64 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.63 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18061379 | 1.00 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL18061371 | 0.93 | ELANE (0.88) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL30637565 | 0.93 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL24075553 | 0.93 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL18061380 | 0.93 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL30637395 | 0.92 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL18037686 | 0.92 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| SCHEMBL18037687 | 0.92 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| Nymphaeol A SCHEMBL7795014 | 0.90 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 | |
| Nymphaeol A SCHEMBL909992 | 0.90 | ELANE (1.00) | ELANEACHEALOX5PTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-09 | — | — | US | disclosed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | ELANE 1548/4885ACHE 2560/4885ALOX5 18/4885 |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | ELANE 1548/4885ACHE 2560/4885ALOX5 18/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | ELANE 1548/4885ACHE 2560/4885ALOX5 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.