Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.66 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.65 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.65 |
| ▸ | XDH | P47989 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | PRKCA | P17252 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513744 | 1.00 | ABCG2 (0.66) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| SCHEMBL5518672 | 0.92 | SLC22A12 (0.77) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| SCHEMBL14523865 | 0.89 | SLC22A12 (0.83) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| SCHEMBL13140976 | 0.84 | SLC22A12 (0.64) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| SCHEMBL3231721 | 0.82 | ABCG2 (0.78) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| SCHEMBL2345203 | 0.80 | ELANE (0.59) | ABCG2ESR1AKR1B10AKR1B1PDPK1 | |
| Sophoraflavanone A SCHEMBL141996 | 0.79 | ABCG2 (1.00) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| Sophoraflavanone A SCHEMBL29624617 | 0.79 | ABCG2 (1.00) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| Isobavachin SCHEMBL31620056 | 0.79 | SLC22A12 (1.00) | ABCG2SLC22A12SLC2A9XDHESR1 | |
| Isobavachin SCHEMBL27013463 | 0.79 | SLC22A12 (1.00) | ABCG2SLC22A12SLC2A9XDHESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | claimed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | claimed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | ABCG2 806/4885SLC22A12 241/4885SLC2A9 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.