SCHEMBL2345255

SCHEMBL2345255

CCOC(=O)C1=CCC1C(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
ALDH1A1 P00352 3/20 0.45
GAA P10253 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.40
POLB P06746 1/20 0.39
TLR4 O00206 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28369299 0.83 MAPT (0.43) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL2345193 0.83 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDLMNATSHR
SCHEMBL17921502 0.81 CA12 (0.39) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL2344344 0.80 TSHR (0.46) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL10632667 0.80 MAPT (0.44) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL819340 0.74 TLR4 (0.39) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL2340043 0.73 KCNH2 (0.49) MAPTALDH1A1GAAKDM4EHPGD
SCHEMBL819433 0.72 GAA (0.40) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL819762 0.71 ALDH1A1 (0.39) MAPTALDH1A1GAAKDM4EMEN1
SCHEMBL18562240 0.71 TLR4 (0.40) MAPTALDH1A1GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617424-B1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME KONICA MINOLTA OPTO INC (JP) 2012-08-15 EP disclosed
US-20110204531-A1 Method of Manufacturing Wafer Lens KONICA MINOLTA OPTO, INC. (JP) 2011-08-25 US disclosed
EP-2202739-A1 Diffraction optical device and optical pickup device using the same Konica Minolta Opto, Inc. (JP) 2010-06-30 EP disclosed
US-20080310284-A1 DIFFRACTIVE OPTICAL ELEMENT AND OPTICAL PICKUP APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-12-18 US disclosed
EP-1617424-A1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME Konica Minolta Opto, Inc. (JP) 2006-01-18 EP disclosed