Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113468 | 0.91 | ALDH1A1 (0.41) | GLP1RALDH1A1TSHREPHX2KDM4E | |
| SCHEMBL26494222 | 0.86 | MEN1 (0.42) | ALDH1A1TSHREPHX2KDM4EMAPK1 | |
| SCHEMBL22526378 | 0.86 | MEN1 (0.42) | ALDH1A1TSHREPHX2KDM4EMAPK1 | |
| SCHEMBL18552064 | 0.86 | GLP1R (0.52) | SMN1; SMN2GLP1REPHX2KDM4E | |
| SCHEMBL23253802 | 0.86 | GLP1R (0.52) | SMN1; SMN2GLP1REPHX2KDM4E | |
| SCHEMBL27115497 | 0.85 | FAAH (0.49) | GLP1RTSHRKDM4EMAPK1HIF1A | |
| SCHEMBL21660550 | 0.85 | KDM4E (0.52) | SMN1; SMN2TSHREPHX2KDM4EMAPK1 | |
| SCHEMBL29908860 | 0.85 | ADRA1A (0.54) | GLP1RTSHREPHX2KDM4EMAPK1 | |
| SCHEMBL12893042 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHREPHX2KDM4E | |
| SCHEMBL14924288 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TSHREPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108662-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | DTX PHARMA, INC. (US) | 2021-06-03 | — | — | WO | disclosed |