SCHEMBL23453055

SCHEMBL23453055

CC(C)(C)OC(=O)NC(C=O)CCCCNCC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSK P43235 16/20 0.54
MAPT P10636 1/20 0.52
CTSL P07711 3/20 0.51
CTSB P07858 3/20 0.51
CTSH P09668 1/20 0.46
SYK P43405 1/20 0.45
KLK7 P49862 1/20 0.45
KLK5 Q9Y337 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4821212 0.88 MAPT (0.66) CTSKMAPTCTSLCTSBSYK
SCHEMBL8311926 0.88 CTSK (0.56) CTSKMAPTCTSLCTSBCTSH
SCHEMBL21904603 0.87 PPARA (0.53) CTSKMAPTKLK7KLK5
SCHEMBL699601 0.85 MAPT (0.61) CTSKMAPTCTSLCTSBSYK
SCHEMBL12247705 0.85 MAPT (0.61) CTSKMAPTCTSLCTSBSYK
SCHEMBL23156912 0.84 CTSK (0.50) CTSKMAPTCTSLCTSBSYK
SCHEMBL4179699 0.84 MAPT (0.62) CTSKMAPTCTSLCTSBCTSH
SCHEMBL28516961 0.84 CTSK (0.57) CTSKMAPTCTSLCTSBCTSH
SCHEMBL7975866 0.82 KLK5 (0.52) CTSKMAPTCTSLCTSBSYK
SCHEMBL23971349 0.82 KLK5 (0.52) CTSKMAPTCTSLCTSBSYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163541-A1 Method for Preparing PNA Oligomer SEASUNBIO MATERIALS (KR) 2021-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163541-A1 Method for Preparing PNA Oligomer NCL, NOD1, POLI CTSK 4075/4885MAPT 2234/4885CTSL 2953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.