Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410862 | 0.74 | ALDH1A1 (0.44) | GAANPC1RAB9A | |
| SCHEMBL10719221 | 0.71 | MEN1 (0.38) | RAB9A | |
| SCHEMBL10123483 | 0.69 | SLC6A3 (0.38) | GAA | |
| SCHEMBL25353157 | 0.67 | ALDH1A1 (0.53) | GAA | |
| SCHEMBL15508826 | 0.67 | GRM4 (0.33) | — | |
| SCHEMBL16995387 | 0.67 | GAA (0.38) | GAANPC1RAB9A | |
| SCHEMBL7954192 | 0.65 | MAPT (0.34) | GAANPC1 | |
| SCHEMBL20976397 | 0.64 | HCAR2 (0.35) | GAANPC1RAB9A | |
| SCHEMBL23996115 | 0.63 | MEN1 (0.32) | — | |
| SCHEMBL17428923 | 0.62 | PDE2A (0.32) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |