Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453746 | 0.96 | DHODH (0.53) | DHODHMAPTLRRK2PIN1 | |
| SCHEMBL23453745 | 0.89 | HAO2 (0.47) | DHODHCSF1RPIN1HAO2 | |
| SCHEMBL23453724 | 0.85 | DHODH (0.48) | DHODHMAPT | |
| SCHEMBL23453714 | 0.79 | NPC1 (0.47) | MAPT | |
| SCHEMBL23453717 | 0.78 | DHODH (0.41) | DHODHCSF1R | |
| SCHEMBL23453756 | 0.78 | CSF1R (0.40) | DHODHCSF1R | |
| SCHEMBL23453710 | 0.75 | — | — | |
| SCHEMBL22609268 | 0.73 | DHODH (0.43) | DHODHMAPT | |
| SCHEMBL22609280 | 0.73 | GSK3A (0.42) | DHODHCSF1RMAPT | |
| SCHEMBL23486293 | 0.72 | HAO2 (0.44) | DHODHHAO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | DHODH 123/4885CSF1R 1887/4885TNIK 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.