Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1GSK3AGSK3BHRH1HRH2HTR7IDH1IDH2IMPA1IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL2345393 | 0.98 | CA4 (0.50) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL119895 | 0.95 | LMNA (0.43) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL15323416 | 0.93 | LMNA (0.41) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL29356844 | 0.93 | LMNA (0.41) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL275858 | 0.93 | CA4 (0.59) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL20456925 | 0.93 | CA4 (0.59) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL692736 | 0.93 | CA4 (0.59) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL119893 | 0.93 | CA4 (0.59) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL15323413 | 0.92 | CA4 (0.53) | CA4MEN1LMNAKMT2ACYP3A4 | |
| Citric Acid SCHEMBL15323746 | 0.92 | MEN1 (0.40) | CA4MEN1LMNAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-1527338-B1 | METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS SOLUTIONS | INSTRUMENTATION LAB CO (US) | 2011-08-31 | — | — | EP | claimed |
| US-7378006-B2 | Aqueous solutions for reducing the rate of oxygen loss, and methods thereof | INSTRUMENTATION LABORATORY COMPANY (US) | 2008-05-27 | — | — | US | claimed |
| JP-2005534031-A | — | — | 2005-11-10 | — | — | JP | claimed |
| EP-1527338-A1 | COMPOSITIONS AND METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS | Instrumentation Laboratory Company (US) | 2005-05-04 | — | — | EP | claimed |
| US-20040137633-A1 | for increasing accuracy and effective life span of an electrochemical sensor system with oxygen-containing calibration solutions | INSTRUMENTATION LABORATORY COMPANY | 2004-07-15 | — | — | US | claimed |
| WO-2004011931-A1 | COMPOSITIONS AND METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS | INSTRUMENTATION LABORATORY COMPANY (US) | 2004-02-05 | — | — | WO | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-104119237-B | Choline salt of selenium-containing compound and its production and use | 深圳福山生物科技有限公司 | 2016-08-31 | — | — | CN | disclosed |
| US-9248087-B2 | Anti-dandruff hair care products with selective active ingredients and a cationic keratin | HENKEL AG & CO. KGAA (DE) | 2016-02-02 | — | — | US | disclosed |
| CN-104119237-A | Choline salts of selenium-containing compounds, preparation method and applications thereof | SHENZHEN FUSHAN BIOLOG TECHNOLOGY CO LTD | 2014-10-29 | — | — | CN | disclosed |
| CN-103936604-A | Selenium compound-containing choline salt, as well as preparation method and applications thereof | SHENZHEN FUSHAN BIOTECHNOLOGY CO LTD | 2014-07-23 | — | — | CN | disclosed |
| US-20040137633-A1 | for increasing accuracy and effective life span of an electrochemical sensor system with oxygen-containing calibration solutions | INSTRUMENTATION LABORATORY COMPANY | 2004-07-15 | — | — | US | disclosed |
| WO-2004011931-A1 | COMPOSITIONS AND METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS | INSTRUMENTATION LABORATORY COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
| US-20020161039-A1 | Crystalline choline ascorbate | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | US | disclosed |
| CN-1373127-A | Crystal choline ascorbate | BASF AG (DE) | 2002-10-09 | — | — | CN | disclosed |
| US-5705482-A | HUMAN GROWTH HORMONE AND LEUCINE-HISTIDINE-LEUCINE TRIPEPTIDE MIXTURE; STORAGE STABILITY; GLANDULAR DISORDERS | NOVO NORDISK A/S (DK) | 1998-01-06 | — | — | US | disclosed |
| US-3980679-A | Process for the manufacture of glycidyl ethers of monohydric or polyhydric phenols, having improved properties | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |