Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987964 | 0.90 | ADRA2C (0.38) | ADRA2CADRA1AADRA1B | |
| SCHEMBL954461 | 0.90 | ADRA2C (0.38) | ADRA2CADRA1AADRA1B | |
| SCHEMBL954462 | 0.90 | ADRA2C (0.38) | ADRA2CADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL953690 | 0.89 | ADRA2C (0.37) | ADRA2CADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL18784069 | 0.89 | ADRA2C (0.37) | ADRA2CADRA1AADRA1B | |
| SCHEMBL2340350 | 0.81 | GAA (0.35) | FFAR4 | |
| SCHEMBL2957662 | 0.80 | ADRA2C (0.35) | ADRA2CADRA1AADRA1B | |
| SCHEMBL2953335 | 0.80 | ADRA2C (0.35) | ADRA2CADRA1AADRA1B | |
| SCHEMBL16472958 | 0.76 | L3MBTL1 (0.38) | ADRA2CADRA1AADRA1B | |
| SCHEMBL23492876 | 0.76 | RAPGEF4 (0.48) | ADRA2CADRA1AADRA1BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215054-B1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS INC (US) | 2011-08-31 | — | — | EP | claimed |