SCHEMBL23458044

SCHEMBL23458044

Cc1ccc(/C=C/C=C/C=C/c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.67
ALDH1A1 P00352 4/20 0.50
MAPT P10636 2/20 0.50
CYP1B1 Q16678 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
TRPA1 O75762 1/20 0.50
LMNA P02545 1/20 0.50
ALOX5 P09917 1/20 0.50
MAPK1 P28482 1/20 0.50
NFE2L2 Q16236 3/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
APP P05067 4/20 0.46
HTT P42858 1/20 0.46
PKM P14618 1/20 0.46
PPARG P37231 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23458194 1.00 MAOB (0.67) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL11544219 0.98 MAOB (0.70) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL1974108 0.98 MAOB (0.70) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL23458019 0.98 MAOB (0.70) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL23458020 0.98 MAOB (0.70) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL29862187 0.90 NFE2L2 (0.56) MAOBMAPTCYP3A4ALOX5NFE2L2
SCHEMBL23458148 0.90 NFE2L2 (0.56) MAOBMAPTCYP3A4ALOX5NFE2L2
SCHEMBL23458017 0.90 NFE2L2 (0.56) MAOBMAPTCYP3A4ALOX5NFE2L2
SCHEMBL700269 0.87 NFE2L2 (0.61) MAOBALDH1A1MAPTCYP1B1CYP3A4
SCHEMBL4585865 0.87 NFE2L2 (0.61) MAOBALDH1A1MAPTCYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons SICPA HOLDING SA (CH) 2025-12-30 US disclosed
US-20240327736-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2024-10-03 US disclosed
US-12031098-B2 Method of marking a petroleum hydrocarbon SICPA HOLDING SA (CH) 2024-07-09 US disclosed
EP-4069807-B1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS SICPA HOLDING SA (CH) 2023-10-04 EP disclosed
US-20230103579-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS SICPA HOLDING SA (CH) 2023-04-06 US disclosed
US-20230029106-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2023-01-26 US disclosed
EP-4069807-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS Sicpa Holding SA (CH) 2022-10-12 EP disclosed
EP-4069806-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON Sicpa Holding SA (CH) 2022-10-12 EP disclosed
WO-2021110525-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS SICPA HOLDING SA (CH) 2021-06-10 WO disclosed
WO-2021110526-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2021-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons CYP4A11, CYP11B1, CYP11A1 MAOB 1867/4885ALDH1A1 444/4885MAPT 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.