SCHEMBL2345812

SCHEMBL2345812

O=C(O)OC(Cl)c1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.43
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
IDO2 Q6ZQW0 2/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CASP1 P29466 1/20 0.40
CYP1A2 P05177 1/20 0.40
CACNA2D1 P54289 2/20 0.38
CACNA1B Q00975 2/20 0.38
CACNB1 Q02641 2/20 0.38
CACNA1G O43497 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
AKR1B1 P15121 1/20 0.38
TSHR P16473 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607561 0.85 ACP3 (0.41) ACP3IDO1TDO2IDO2ALDH1A1
SCHEMBL10876491 0.85 CASP1 (0.40) ACP3IDO1TDO2IDO2ALDH1A1
SCHEMBL722955 0.83 IDO1 (0.41) ACP3IDO1TDO2IDO2CYP3A4
SCHEMBL7083023 0.80 HCAR2 (0.50) ACP3IDO1TDO2IDO2ALDH1A1
SCHEMBL27545605 0.80 HCAR2 (0.50) ACP3IDO1TDO2IDO2ALDH1A1
SCHEMBL8906867 0.79 LPAR1 (0.49) ACP3IDO1TDO2IDO2ALDH1A1
SCHEMBL10894345 0.79 CASP1 (0.39) ACP3ALDH1A1CASP1TSHRLMNA
SCHEMBL11167494 0.78 CASP1 (0.48) ACP3ALDH1A1CASP1OPRM1OPRL1
SCHEMBL23293691 0.77 LPAR1 (0.39) MEN1KMT2ACASP1AKR1B1MAPT
SCHEMBL8741294 0.77 ACP3 (0.40) ACP3IDO1TDO2IDO2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119562991-A Thermoplastic composition for laser direct structuring MCE技术中心有限公司 2025-03-04 CN disclosed
CN-113234054-A Dialkyl carbonates, methods of making and using the same 亨斯迈石油化学有限责任公司 2021-08-10 CN disclosed
CN-108586254-B Process for producing diaryl carbonate and process for producing aromatic polycarbonate 旭化成株式会社 2021-06-18 CN disclosed
CN-106255683-A Dialkyl carbonates, methods of making and using the same 亨斯迈石油化学有限责任公司 2016-12-21 CN disclosed
EP-1640357-B1 METHOD FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-31 EP disclosed
US-7652122-B2 Method for producing an aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-26 US disclosed
CN-100453520-C Method for producing aromatic carbonate ASAHI CHEMICAL CORP (JP) 2009-01-21 CN disclosed
US-20070055042-A1 Method for producing an aromatic carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
CN-1839112-A Method for producing aromatic carbonate ASAHI CHEMICAL CORP (JP) 2006-09-27 CN disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed