Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251175 | 0.84 | SRD5A2 (0.61) | LMNAMAPTSRD5A2CYP3A4NR1I2 | |
| SCHEMBL216171 | 0.84 | SRD5A2 (0.61) | LMNAMAPTSRD5A2CYP3A4NR1I2 | |
| SCHEMBL14694447 | 0.80 | LMNA (0.98) | LMNAMAPTCYP3A4NR1I2PGR | |
| SCHEMBL11232680 | 0.80 | SRD5A2 (0.56) | LMNAMAPTSRD5A2CYP3A4NR1I2 | |
| SCHEMBL17537539 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR | |
| SCHEMBL11429123 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR | |
| SCHEMBL17541885 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR | |
| Testosterone Enanthate SCHEMBL19644909 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR | |
| SCHEMBL17541905 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR | |
| Testosterone Undecanoate SCHEMBL17545317 | 0.80 | LMNA (1.00) | LMNAMAPTCYP3A4NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110987-A1 | METHODS AND APPARATUSES FOR DIAGNOSING CANCER FROM CELL-FREE NUCLEIC ACIDS | LIFE & SOFT (FR) | 2021-06-10 | — | — | WO | disclosed |