SCHEMBL216171

SCHEMBL216171

CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=C(Cl)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.61
SHBG P04278 1/20 0.52
CYP19A1 P11511 7/20 0.51
CYP2C19 P33261 2/20 0.50
CYP3A4 P08684 4/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
NR1I2 O75469 2/20 0.49
TSHR P16473 2/20 0.49
NR3C1 P04150 1/20 0.49
CYP17A1 P05093 1/20 0.49
PGR P06401 1/20 0.49
AR P10275 1/20 0.49
CYP2C9 P11712 1/20 0.49
OPRK1 P41145 1/20 0.49
MAPK1 P28482 2/20 0.48
MEN1 O00255 1/20 0.48
ALOX15 P16050 1/20 0.48
BRCA1 P38398 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2251175 1.00 SRD5A2 (0.61) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL3102374 0.89 CYP3A4 (0.59) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL3102365 0.89 CYP3A4 (0.59) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL23458225 0.89 CYP3A4 (0.64) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL11821082 0.88 SHBG (0.68) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL11232680 0.87 SRD5A2 (0.56) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL23458371 0.84 LMNA (0.66) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL8340076 0.83 SHBG (0.48) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL8340073 0.83 SHBG (0.48) SRD5A2SHBGCYP19A1CYP2C19CYP3A4
SCHEMBL11873307 0.83 SRD5A2 (0.45) SRD5A2SHBGCYP19A1CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992431-B2 Inserter BAYER OY (FI) 2024-05-28 US claimed
US-20210298942-A1 INSERTER BAYER OY (FI) 2021-09-30 US claimed
US-10561524-B2 Inserter BAYER OY (FI) 2020-02-18 US claimed
EP-3501543-A1 METHOD FOR MANUFACTURING VAGINAL DRUG DELIVERY SYSTEMS USING A THREE DIMENSIONAL PRINTER Delim Cosmetics & Pharma S.r.l. (IT) 2019-06-26 EP claimed
US-20170196728-A1 INSERTER BAYER OY (FI) 2017-07-13 US claimed
US-20100322884-A1 METHOD AND COMPOSITION FOR TRANSDERMAL DRUG DELIVERY ACRUX DDS PTY LTD 2010-12-23 US claimed
EP-1402924-B1 Use of a compound for the treatment of heart hypertrophy FRAUNHOFER GES FORSCHUNG (DE) 2008-12-31 EP claimed
EP-1904031-A2 A SUBSTANTIALLY WATER-FREE PRESSURISED PROPELLANT MIXTURE THERAPICON SRL (IT) 2008-04-02 EP claimed
US-20070292479-A1 Film-shaped drug forms for use in the oral cavity (wafers) BAYER SCHERING PHARMA AG (DE) 2007-12-20 US claimed
WO-2006122905-A2 A SUBSTANTIALLY WATER-FREE PRESSURISED PROPELLANT MIXTURE THERAPICON SRL (IT) 2006-11-23 WO claimed
EP-1282402-B1 STABILIZED AQUEOUS SUSPENSIONS FOR PARENTERAL USE PHARMACIA ITALIA SPA (IT) 2005-12-21 EP claimed
US-6495534-B2 Stabilized aqueous suspensions for parenteral use PHARMACIA & UPJOHN SPA (IT) 2002-12-17 US claimed
WO-2025226786-A1 METHODS AND COMPOSITIONS COMPRISING WETTABLE ELECTROSPUN MATRIX POLY-MED, INC. (US) 2025-10-30 WO disclosed
US-20250289909-A1 FUNCTIONALIZED AND CROSSLINKED POLYMERS PMIDG LLC (US) 2025-09-18 US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 US disclosed
US-12351656-B2 Functionalized and crosslinked polymers PMIDG, LLC (US) 2025-07-08 US disclosed
EP-0597071-A1 ANDROGENS FOR STIMULATING THE CENTRAL NERVOUS SYSTEM AND FOR TREATING OSTEOPOROSIS ARROWDEAN LTD. (IE) 1994-05-18 EP disclosed
EP-0597071-A1 ANDROGENS FOR STIMULATING THE CENTRAL NERVOUS SYSTEM AND FOR TREATING OSTEOPOROSIS ARROWDEAN LTD. (IE) 1994-05-18 EP disclosed
WO-1993024128-A1 ANDROGENS FOR STIMULATING THE CENTRAL NERVOUS SYSTEM AND FOR TREATING OSTEOPOROSIS MATTERN ET PARTNER PHARMAZEUTISCHE ENTWICKLUNGS- UND HANDELSGES. MBH (DE) 1993-12-09 WO disclosed
WO-1993024128-A1 ANDROGENS FOR STIMULATING THE CENTRAL NERVOUS SYSTEM AND FOR TREATING OSTEOPOROSIS MATTERN ET PARTNER PHARMAZEUTISCHE ENTWICKLUNGS- UND HANDELSGES. MBH (DE) 1993-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100322884-A1 METHOD AND COMPOSITION FOR TRANSDERMAL DRUG DELIVERY CUTA, TSLP, CERT1 SRD5A2 1338/4885SHBG 252/4885CYP19A1 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.