SCHEMBL23458440

SCHEMBL23458440

O=C(Nc1nccnc1Cl)c1ccncc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.56
GAA P10253 1/20 0.55
TYK2 P29597 2/20 0.54
KMT2A Q03164 2/20 0.51
NT5E P21589 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
KCNMA1 Q12791 1/20 0.49
MPO P05164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2A6 P11509 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520680 0.77 RAB9A (0.77) GAATYK2KMT2ALMNAPOLB
SCHEMBL22583515 0.74 SMN1; SMN2 (0.39) GAAKMT2ALMNAPOLBKDM4E
SCHEMBL6612630 0.72 HTT (0.56) GAATYK2KMT2ALMNAPOLB
SCHEMBL23458490 0.72 KCNMA1 (0.52) MAPK1GAATYK2KMT2ANT5E
SCHEMBL15645765 0.72 TYK2 (0.54) MAPK1GAATYK2KMT2ANT5E
SCHEMBL11372296 0.72 PTK2 (0.43) GAAPOLBKDM4EL3MBTL1SMN1; SMN2
SCHEMBL11617697 0.71 MAPK1 (1.00) MAPK1GAATYK2KMT2ANT5E
SCHEMBL1898755 0.71 GAA (0.91) MAPK1GAATYK2KMT2ANT5E
SCHEMBL19242053 0.71 GAA (1.00) MAPK1GAATYK2KMT2ANT5E
SCHEMBL23330837 0.71 KCNMA1 (0.51) MAPK1GAATYK2KMT2ANT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed