SCHEMBL23458481

SCHEMBL23458481

c1cnc2nc(-c3ccncc3)sc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
IDO1 P14902 3/20 0.46
TDO2 P48775 3/20 0.46
CYP19A1 P11511 3/20 0.41
PIK3CD O00329 1/20 0.41
PIK3CA P42336 1/20 0.41
PIK3CB P42338 1/20 0.41
PIK3CG P48736 1/20 0.41
CDC7 O00311 5/20 0.40
DBF4 Q9UBU7 5/20 0.40
MAPK14 Q16539 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AR P10275 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749417 0.87 NPC1 (0.47) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL29064014 0.85 KDM4E (0.46) KDM4ENPC1RAB9ACYP19A1ALDH1A1
SCHEMBL5311147 0.83 APP (0.42) KDM4ENPC1RAB9ACYP19A1ALDH1A1
SCHEMBL23172529 0.83 RAB9A (0.40) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL15747062 0.83 ALOX5 (0.43) KDM4ENPC1RAB9AALDH1A1TP53
SCHEMBL12910392 0.79 RAB9A (0.43) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL13189380 0.79 APP (0.61) KMT2AMAPT
SCHEMBL15746019 0.79 TNF (0.61) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL23502882 0.78 BCHE (0.39) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL23458477 0.77 KDM4E (0.49) KDM4ENPC1RAB9AIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed