SCHEMBL23486249

SCHEMBL23486249

O=C(O)CC[n+]1ccc(-c2nc3ncncc3s2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.34
PTGDR2 Q9Y5Y4 3/20 0.32
POLB P06746 1/20 0.32
NFKB1 P19838 2/20 0.31
NFKB2 Q00653 2/20 0.31
RELA Q04206 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
P4HTM Q9NXG6 1/20 0.31
ALDH1A1 P00352 2/20 0.30
PPARG P37231 1/20 0.30
NCOA2 Q15596 1/20 0.30
NCOA1 Q15788 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
STAT1 P42224 1/20 0.30
RAB9A P51151 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23458577 0.99 KDM4E (0.33) KDM4EPTGDR2POLBNFKB1NFKB2
SCHEMBL23458575 0.89
SCHEMBL23486113 0.83 DYRK1A (0.35) KDM4EALDH1A1
Bromide SCHEMBL23458489 0.82 DYRK1A (0.34)
SCHEMBL23486270 0.81 KDM4E (0.37) KDM4EPTGDR2POLBNFKB1NFKB2
SCHEMBL23486246 0.81 S1PR1 (0.37) KDM4EPTGDR2POLBNFKB1NFKB2
SCHEMBL23486136 0.77 PTGDR2 (0.34) KDM4EPTGDR2POLBLMNAALDH1A1
SCHEMBL23486258 0.74 KDM4E (0.52) KDM4EPOLBNFKB1NFKB2RELA
SCHEMBL23458477 0.72 KDM4E (0.49) KDM4EPOLBALDH1A1NPC1HPGD
SCHEMBL23197341 0.71 KDM4E (0.34) KDM4EPTGDR2POLBALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed