Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458593 | 0.90 | BUB1 (0.34) | PDPK1 | |
| SCHEMBL29838663 | 0.90 | BUB1 (0.34) | PDPK1 | |
| SCHEMBL28914081 | 0.87 | PDPK1 (0.33) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL28879193 | 0.81 | PDPK1 (0.42) | PDPK1GBA1 | |
| SCHEMBL28569915 | 0.81 | MCL1 (0.32) | PDPK1GBA1 | |
| SCHEMBL28412517 | 0.78 | ADORA3 (0.36) | ADORA3 | |
| SCHEMBL31123773 | 0.77 | BUB1 (0.34) | PDPK1GBA1 | |
| SCHEMBL31123801 | 0.77 | BUB1 (0.34) | PDPK1GBA1 | |
| SCHEMBL19715023 | 0.74 | PDPK1 (0.36) | PDPK1GBA1 | |
| SCHEMBL18009865 | 0.73 | BUB1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069698-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | Lupin Limited (IN) | 2022-10-12 | — | — | EP | disclosed |
| CN-115135651-A | Substituted nucleoside analogs as PRMT5 inhibitors | 鲁皮恩有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2021111322-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | LUPIN LIMITED (IN) | 2021-06-10 | — | — | WO | disclosed |