Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123801 | 1.00 | BUB1 (0.34) | BUB1BCHEHSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL28914081 | 0.91 | PDPK1 (0.33) | PDPK1GBA1 | |
| SCHEMBL23458593 | 0.87 | BUB1 (0.34) | BUB1BCHEHSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL29838663 | 0.87 | BUB1 (0.34) | BUB1BCHEHSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL19714886 | 0.81 | PDPK1 (0.42) | BUB1BCHEHSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL23458592 | 0.77 | MEN1 (0.32) | PDPK1GBA1 | |
| SCHEMBL18009865 | 0.77 | BUB1 (0.34) | BUB1BCHEHSP90AA1HSP90AB1PIK3CD | |
| SCHEMBL21683427 | 0.76 | HSP90AA1 (0.38) | BUB1BCHEHSP90AA1HSP90AB1PIK3CD | |
| SCHEMBL19730196 | 0.73 | HTR6 (0.36) | BUB1BCHEHSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL30002876 | 0.72 | JAK1 (0.39) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |