Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838663 | 1.00 | BUB1 (0.34) | BUB1HSP90AA1HSP90AB1L3MBTL1GPR119 | |
| SCHEMBL23458592 | 0.90 | MEN1 (0.32) | PDPK1 | |
| SCHEMBL31123801 | 0.87 | BUB1 (0.34) | BUB1HSP90AA1HSP90AB1PIK3CDABL1 | |
| SCHEMBL31123773 | 0.87 | BUB1 (0.34) | BUB1HSP90AA1HSP90AB1PIK3CDABL1 | |
| SCHEMBL19714886 | 0.81 | PDPK1 (0.42) | BUB1HSP90AA1HSP90AB1GPR119PIK3CD | |
| SCHEMBL18009865 | 0.81 | BUB1 (0.34) | BUB1HSP90AA1HSP90AB1L3MBTL1GPR119 | |
| SCHEMBL17528555 | 0.80 | HSP90AA1 (0.41) | BUB1HSP90AA1HSP90AB1L3MBTL1GPR119 | |
| SCHEMBL17528558 | 0.78 | CRHR1 (0.35) | BUB1HSP90AA1HSP90AB1EGFRKDR | |
| SCHEMBL21683427 | 0.77 | HSP90AA1 (0.38) | BUB1HSP90AA1HSP90AB1PIK3CDABL1 | |
| SCHEMBL28914081 | 0.77 | PDPK1 (0.33) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230066014-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | LUPIN LIMITED (IN) | 2023-03-02 | — | — | US | disclosed |
| EP-4069698-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | Lupin Limited (IN) | 2022-10-12 | — | — | EP | disclosed |
| WO-2021111322-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | LUPIN LIMITED (IN) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230066014-A1 | SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT3 | BUB1 2716/4885HSP90AA1 4751/4885HSP90AB1 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.