SCHEMBL234621

SCHEMBL234621

CCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 1.00
▸ NR5A2 O00482 1/20 1.00
▸ NR5A1 Q13285 1/20 1.00
▸ MAPT P10636 3/20 0.88
▸ FABP3 P05413 1/20 0.78
▸ RECQL P46063 1/20 0.77
▸ ALDH1A1 P00352 1/20 0.68
▸ ADRA1D P25100 1/20 0.66
▸ PTAFR P25105 1/20 0.66
▸ HTR1D P28221 1/20 0.66
▸ HTR2C P28335 1/20 0.66
▸ ADRA1B P35368 1/20 0.66
▸ DRD3 P35462 1/20 0.66
▸ TMEM97 Q5BJF2 1/20 0.66
▸ LPAR3 Q9UBY5 3/20 0.63
▸ LPAR1 Q92633 2/20 0.63
▸ ENPP2 Q13822 1/20 0.63
▸ MAPK1 P28482 3/20 0.60
▸ MEN1 O00255 2/20 0.60
▸ GMNN O75496 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235513 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
Colfosceril Palmitate SCHEMBL184776 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL233979 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL234757 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL22693933 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL17165029 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL237094 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL2135188 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL233582 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL235645 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599605-B2 Uric acid liposomes HOSPITAL CLINIC DE BARCELONA (ES) 2026-04-14 — — US claimed
US-20250360200-A1 VACCINE COMPOSITIONS AND USES THEREOF UNIV MICHIGAN REGENTS (US) 2025-11-27 — — US claimed
CN-120009446-A Lipidomic method for distinguishing green tea of different varieties 中南民族大学 2025-05-16 — — CN claimed
EP-4531931-A1 VACCINE COMPOSITIONS AND USES THEREOF The Regents of The University of Michigan (US) 2025-04-09 — — EP claimed
US-20240390381-A1 URIC ACID LIPOSOMES AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, M.P. (ES) 2024-11-28 — — US claimed
US-20240382626-A1 IRRADIATION AMENABLE LIPOSOMAL DYE AGGREGATES AND METHODS OF SYNTHESIS AND USE THEREOF UNIV TEXAS (US) 2024-11-21 — — US claimed
CN-113848261-B Identification method of fungi based on lipidomic 中南民族大学 2024-08-27 — — CN claimed
US-20240180868-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRUS INFECTION, THE PHARMACEUTICAL COMPOSITION COMPRISING ROTTLERIN AS ACTIVE INGREDIENT QVET (KR) 2024-06-06 — — US claimed
WO-2024053974-A1 COMPOSITION FOR PHOTOTHERMAL THERAPY AND PREPARATION METHOD THEREFOR 서울대학교산학협력단 2024-03-14 — — WO claimed
EP-4321158-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTIONS, CONTAINING ROTTLERIN AS ACTIVE INGREDIENT Qvet (KR) 2024-02-14 — — EP claimed
EP-3285814-A1 IMAGING OF TUMOR-ASSOCIATED MACROPHAGES Memorial Sloan-Kettering Cancer Center (US) 2018-02-28 — — EP claimed
US-20170319719-A1 J-Aggregate Forming Nanoparticle UNIVERSITY HEALTH NETWORK (CA) 2017-11-09 — — US claimed
WO-2016186429-A1 COMPOSITION FOR CANCER TREATMENT COMPRISING INDOCYANINE GREEN-LIPOSOME COMPOSITE 고려대학교산학협력단 2016-11-24 — — WO claimed
WO-2016172146-A1 IMAGING OF TUMOR-ASSOCIATED MACROPHAGES MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2016-10-27 — — WO claimed
US-20150359912-A1 J-Aggregate Forming Nanoparticle UNIVERSITY HEALTH NETWORK (CA) 2015-12-17 — — US claimed
US-20070014842-A1 Pharmaceutical liposomal compositions ID BIOMEDICAL CORPORATION OF QUEBEC C.O.B. AS GLAXOSMITHKLINE BIOLOGICALS NORTH AMERICA (CA) 2007-01-18 — — US claimed
US-20070014841-A1 Pharmaceutical compositions ID BIOMEDICAL CORPORATION OF QUEBEC C.O.B. AS GLAXOSMITHKLINE BIOLOGICALS NORTH AMERICA (CA) 2007-01-18 — — US claimed
EP-1536831-A2 PHARMACEUTICAL LIPOSOMAL COMPOSITIONS CONTAINING N. MENINGITIDIS DERIVED POLYPEPTIDES OR POLYNUCLEOTIDES ID Biomedical Corporation (CA) 2005-06-08 — — EP claimed
US-20040132652-A1 Pharmaceutical compositions SHIRE BIOCHEM INC. (CA) 2004-07-08 — — US claimed
WO-2004019976-A2 PHARMACEUTICAL LIPOSOMAL COMPOSITIONS CONTAINING N. MENINGITIDIS DERIVED POLYPEPTIDES OR POLYNUCLEOTIDES ID BIOMEDICAL CORPORATION (CA) 2004-03-11 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070014842-A1 Pharmaceutical liposomal compositions NGLY1, PHOSPHO1, LPXN SMN1; SMN2 1933/4885NR5A2 2921/4885NR5A1 3363/4885
US-12599605-B2 Uric acid liposomes CASP2, HTRA2, CASP10 SMN1; SMN2 1112/4885NR5A2 4531/4885NR5A1 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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