Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 18/20 | 0.52 |
| ▸ | CRY2 | Q49AN0 | 17/20 | 0.52 |
| ▸ | CRY1 | Q16526 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423589 | 0.83 | CRY2 (0.58) | PER2CRY2CRY1 | |
| SCHEMBL29623020 | 0.79 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL28398765 | 0.77 | CRY2 (0.62) | PER2CRY2CRY1 | |
| SCHEMBL29448051 | 0.77 | CRY2 (0.62) | PER2CRY2CRY1 | |
| SCHEMBL29448056 | 0.76 | BACE1 (0.53) | PER2CRY2CRY1 | |
| SCHEMBL28429472 | 0.76 | BACE1 (0.53) | PER2CRY2CRY1 | |
| SCHEMBL8175096 | 0.75 | BACE1 (0.60) | PER2CRY2CRY1 | |
| SCHEMBL8175105 | 0.75 | BACE1 (0.60) | PER2CRY2CRY1 | |
| SCHEMBL8182522 | 0.75 | BACE1 (0.60) | PER2CRY2CRY1 | |
| SCHEMBL28406050 | 0.73 | CRY2 (0.64) | PER2CRY2CRY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939971-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-3129366-B1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | SYNCHRONICITY PHARMA INC (US) | 2021-06-09 | — | — | EP | disclosed |