Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | PER2 | O15055 | 14/20 | 0.52 |
| ▸ | CRY2 | Q49AN0 | 14/20 | 0.52 |
| ▸ | CRY1 | Q16526 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448056 | 1.00 | BACE1 (0.53) | BACE1PER2CRY2CRY1ALDH1A1 | |
| SCHEMBL28423589 | 0.92 | CRY2 (0.58) | PER2CRY2CRY1 | |
| SCHEMBL28425309 | 0.88 | BACE1 (0.71) | BACE1PER2CRY2CRY1DNM1 | |
| SCHEMBL29623019 | 0.88 | BACE1 (0.71) | BACE1PER2CRY2CRY1DNM1 | |
| SCHEMBL29622976 | 0.88 | BACE1 (0.71) | BACE1PER2CRY2CRY1DNM1 | |
| SCHEMBL29623035 | 0.85 | PER2 (0.47) | BACE1PER2CRY2CRY1ALDH1A1 | |
| SCHEMBL29623039 | 0.85 | PER2 (0.47) | BACE1PER2CRY2CRY1ALDH1A1 | |
| SCHEMBL11788371 | 0.85 | BACE1 (0.70) | BACE1PER2CRY2CRY1ALDH1A1 | |
| SCHEMBL30145436 | 0.85 | BACE1 (0.70) | BACE1PER2CRY2CRY1ALDH1A1 | |
| SCHEMBL28410416 | 0.84 | DNM1 (0.62) | PER2CRY2CRY1ALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285793-B | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-04-22 | — | — | CN | disclosed |
| CN-111285793-A | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-06-16 | — | — | CN | disclosed |