Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472083 | 0.85 | SLC2A1 (0.40) | SLC2A1CYP3A4CYP1A2LMNATLR7 | |
| SCHEMBL20219767 | 0.84 | TLR7 (0.44) | CYP3A4CYP1A2TLR7TLR8 | |
| SCHEMBL23472214 | 0.83 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL20219660 | 0.82 | TLR7 (0.49) | CYP3A4CYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL23472249 | 0.80 | PDE5A (0.40) | CYP3A4CYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL23472141 | 0.79 | SMN1; SMN2 (0.50) | LMNATSHRMAPK1MAPTHSD17B10 | |
| SCHEMBL23472630 | 0.76 | MAPT (0.39) | CYP3A4CYP1A2ALDH1A1LMNATLR7 | |
| SCHEMBL20219424 | 0.76 | TLR7 (0.45) | CYP1A2TLR7TLR8 | |
| SCHEMBL15470097 | 0.75 | TLR7 (0.47) | CYP3A4CYP1A2CYP2D6CYP2C9TLR7 | |
| SCHEMBL20219267 | 0.74 | TLR7 (0.44) | CYP3A4CYP1A2CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |