Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472630 | 0.92 | MAPT (0.39) | TLR7TLR8CYP1A2CYP3A4LMNA | |
| SCHEMBL20219767 | 0.89 | TLR7 (0.44) | TLR7TLR8CYP1A2CYP3A4 | |
| SCHEMBL23472305 | 0.86 | TLR7 (0.44) | TLR7TLR8CYP1A2CYP3A4 | |
| SCHEMBL23472391 | 0.85 | SLC2A1 (0.41) | SLC2A1TLR7TLR8CYP1A2CYP3A4 | |
| SCHEMBL13195680 | 0.82 | FLT3 (0.41) | TLR7TLR8CYP1A2CYP3A4MAPT | |
| SCHEMBL23472210 | 0.82 | MTNR1B (0.47) | TLR7TLR8MAPT | |
| SCHEMBL23472201 | 0.82 | TLR7 (0.51) | TLR7TLR8CYP1A2 | |
| SCHEMBL23472466 | 0.81 | CYP1A2 (0.45) | TLR7TLR8CYP1A2CYP3A4LMNA | |
| SCHEMBL20219401 | 0.81 | ALDH1A1 (0.43) | TLR7TLR8CYP1A2LMNA | |
| SCHEMBL23472163 | 0.81 | TLR7 (0.49) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |