Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472141 | 0.88 | SMN1; SMN2 (0.50) | LMNA | |
| SCHEMBL23472512 | 0.83 | TLR7 (0.38) | PDE5AALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL20219500 | 0.82 | CYP1A2 (0.47) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15470083 | 0.82 | TLR8 (0.47) | ALDH1A1CYP3A4CYP2C19TLR8TLR7 | |
| SCHEMBL20219267 | 0.81 | TLR7 (0.44) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23472065 | 0.80 | TLR8 (0.43) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23472391 | 0.80 | SLC2A1 (0.41) | PDE5AALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL23472382 | 0.80 | TLR8 (0.43) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20219660 | 0.80 | TLR7 (0.49) | ALDH1A1LMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23472276 | 0.79 | TLR7 (0.37) | ALDH1A1LMNATLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |