Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219322 | 0.86 | CYP1A2 (0.42) | KMT2ALMNATLR7TLR8CYP1A2 | |
| SCHEMBL23472630 | 0.85 | MAPT (0.39) | KMT2AMAPTLMNATLR7TLR8 | |
| SCHEMBL15470097 | 0.85 | TLR7 (0.47) | TLR7TLR8CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23472423 | 0.84 | MEN1 (0.45) | KMT2AMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL20219406 | 0.80 | S1PR4 (0.35) | KMT2AMAPTLMNATLR7TLR8 | |
| SCHEMBL20219444 | 0.79 | TLR7 (0.42) | LMNATLR7TLR8CYP1A2CYP3A4 | |
| SCHEMBL23472083 | 0.78 | SLC2A1 (0.40) | KMT2AMAPTLMNATLR7TLR8 | |
| SCHEMBL23472305 | 0.78 | TLR7 (0.44) | TLR7TLR8CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL20219767 | 0.77 | TLR7 (0.44) | TLR7TLR8CYP1A2CYP3A4 | |
| SCHEMBL15470064 | 0.77 | TLR7 (0.53) | TLR7TLR8CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |