Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219408 | 0.85 | TLR8 (0.42) | L3MBTL1TLR8TLR7 | |
| SCHEMBL23472437 | 0.80 | KMT2A (0.37) | MAPTALDH1A1ATMHPGDSTK17A | |
| SCHEMBL23472263 | 0.79 | S1PR4 (0.47) | S1PR4MAPTALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL20219444 | 0.78 | TLR7 (0.42) | STK17ATLR8TLR7STK17BLMNA | |
| SCHEMBL23472423 | 0.77 | MEN1 (0.45) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL15470068 | 0.76 | L3MBTL1 (0.45) | S1PR4MAPTALDH1A1L3MBTL1RAB9A | |
| SCHEMBL23472434 | 0.74 | CYP2D6 (0.40) | MAPTALDH1A1RAB9ATLR8TLR7 | |
| SCHEMBL23472461 | 0.73 | TLR8 (0.43) | L3MBTL1TLR8TLR7 | |
| SCHEMBL20219702 | 0.72 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1TLR8TLR7MEN1 | |
| SCHEMBL20219322 | 0.72 | CYP1A2 (0.42) | ALDH1A1RAB9ASTK17ATLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |