SCHEMBL23479671

SCHEMBL23479671

O=C(O)c1cccc(-c2ccccc2OC2OC(CO)C(O)C(O)C2O)c1

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SELP P16109 2/20 0.56
SELPLG Q14242 1/20 0.56
TYR P14679 1/20 0.55
NPC1 O15118 1/20 0.54
USP2 O75604 1/20 0.54
TNNI3 P19429 1/20 0.54
TNNT2 P45379 1/20 0.54
RAB9A P51151 1/20 0.54
TNNC1 P63316 1/20 0.54
HKDC1 Q2TB90 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7035249 1.00 SELP (0.56) SELPSELPLGTYRNPC1USP2
SCHEMBL23479703 1.00 SELP (0.56) SELPSELPLGTYRNPC1USP2
SCHEMBL7035257 1.00 SELP (0.56) SELPSELPLGTYRNPC1USP2
SCHEMBL23479746 1.00 SELP (0.56) SELPSELPLGTYRNPC1USP2
SCHEMBL7030131 0.88 TYR (0.57) TYR
SCHEMBL7030124 0.88 TYR (0.57) TYR
SCHEMBL23479673 0.88 TYR (0.58) TYR
SCHEMBL7030619 0.88 TYR (0.58) TYR
SCHEMBL7030610 0.88 TYR (0.58) TYR
SCHEMBL23479694 0.88 TYR (0.58) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773127-B2 Compounds and methods for treating bacterial infections WASHINGTON UNIVERSITY (US) 2023-10-03 US disclosed
US-11773127-B2 Compounds and methods for treating bacterial infections WASHINGTON UNIVERSITY (US) 2023-10-03 US disclosed
US-20210171563-A1 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS WASHINGTON UNIVERSITY (US) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171563-A1 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS MMP8, ELANE, MPO SELP 442/4885SELPLG 2884/4885TYR 273/4885
US-11773127-B2 Compounds and methods for treating bacterial infections MMP8, ELANE, MPO SELP 442/4885SELPLG 2884/4885TYR 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.