Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480274 | 0.91 | SLC26A3 (0.43) | KMT2A | |
| SCHEMBL23472052 | 0.84 | CYP1A1 (0.43) | KDM4EHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL23471908 | 0.84 | KDM4E (0.42) | KDM4EHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL23471909 | 0.78 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL23480242 | 0.76 | CYP2D6 (0.40) | KDM4EHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL23472098 | 0.76 | CYP1A1 (0.44) | KMT2A | |
| SCHEMBL23472064 | 0.75 | SLC26A3 (0.42) | — | |
| SCHEMBL23472100 | 0.69 | SLC26A3 (0.48) | KMT2A | |
| SCHEMBL23472102 | 0.69 | SLC26A3 (0.39) | KDM4EHPGDALDH1A1HSD17B10RAB9A | |
| SCHEMBL12371398 | 0.67 | MAPT (0.42) | KDM4EHPGDALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110834-A2 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | ETH ZURICH (CH) | 2021-06-10 | — | — | WO | disclosed |