SCHEMBL2348201

SCHEMBL2348201

CCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARB P10826 15/20 1.00
RARA P10276 2/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
MAPT P10636 1/20 1.00
MTOR P42345 1/20 1.00
KMT2A Q03164 1/20 1.00
NPC1 O15118 1/20 0.67
NFKB1 P19838 1/20 0.67
RAB9A P51151 1/20 0.67
NFKB2 Q00653 1/20 0.67
RELA Q04206 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
RARG P13631 1/20 0.64
THRA P10827 1/20 0.61
THRB P10828 1/20 0.61
PLA2G1B P04054 1/20 0.60
ATG4B Q9Y4P1 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11113720 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL2402567 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL7542464 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL8533917 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL8531633 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL23484727 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL4174144 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL3088908 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL8536621 1.00 RARB (1.00) RARBRARAMEN1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL6024255 0.98 RARB (0.97) RARBRARAMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114149616-B Heat conducting filler, preparation method, resin composite material containing heat conducting filler and application of resin composite material 全球能源互联网研究院有限公司 2023-11-28 CN claimed
CN-114149616-A Heat-conducting filler, preparation method, resin composite material containing heat-conducting filler and application of resin composite material 全球能源互联网研究院有限公司 2022-03-08 CN claimed
CN-114149616-B Heat conducting filler, preparation method, resin composite material containing heat conducting filler and application of resin composite material 全球能源互联网研究院有限公司 2023-11-28 CN disclosed
US-20220296579-A1 COMPOSITIONS AND METHODS FOR PROVIDING CARDIOPROTECTIVE EFFECTS CORNELL UNIVERSITY (US) 2022-09-22 US disclosed
CN-114149616-A Heat-conducting filler, preparation method, resin composite material containing heat-conducting filler and application of resin composite material 全球能源互联网研究院有限公司 2022-03-08 CN disclosed
US-11191755-B2 Compositions and methods for providing cardioprotective effects CORNELL UNIVERSITY (US) 2021-12-07 US disclosed
US-11160769-B2 Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists CORNELL UNIVERSITY (US) 2021-11-02 US disclosed
US-10611786-B2 Manganese (III) catalyzed C—H aminations THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2020-04-07 US disclosed
CN-106854194-B Photosensitive material and optical device 财团法人工业技术研究院 2019-12-06 CN disclosed
US-20190106448-A1 MANGANESE (III) CATALYZED C--H AMINATIONS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-04-11 US disclosed
US-9976085-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
WO-1998046563-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-10-22 WO disclosed
EP-0341686-B1 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORP (JP) 1994-08-17 EP disclosed
US-5098602-A Aromatic ester derivatives and fluorophenol ketones NIPPON MINING CO., LTD. (JP) 1992-03-24 US disclosed
EP-0341686-A2 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORPORATION (JP) 1989-11-15 EP disclosed
US-4708441-A LIQUID CRYSTALS HOFFMAN-LA ROCHE INC. (US) 1987-11-24 US disclosed
US-4550981-A Liquid crystalline esters and mixtures HOFFMANN-LA ROCHE INC. (US) 1985-11-05 US disclosed
US-4136053-A BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) 1979-01-23 US disclosed
US-4073742-A Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-14 US disclosed
US-4065489-A Biphenyl esters and liquid crystalline mixtures comprising them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220296579-A1 COMPOSITIONS AND METHODS FOR PROVIDING CARDIOPROTECTIVE EFFECTS RARB, RARG, RARA RARB 1/4885RARA 3/4885MEN1 4881/4885
US-11191755-B2 Compositions and methods for providing cardioprotective effects RARB, RARG, RARA RARB 1/4885RARA 3/4885MEN1 4881/4885
US-11160769-B2 Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists RARA, RARG, RXRA RARB 5/4885RARA 1/4885MEN1 3112/4885
US-10611786-B2 Manganese (III) catalyzed C—H aminations HLCS, NCL, NUDC RARB 1228/4885RARA 1977/4885MEN1 180/4885
US-20190106448-A1 MANGANESE (III) CATALYZED C--H AMINATIONS HLCS, NCL, NUDC RARB 886/4885RARA 1482/4885MEN1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.