Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TCF4 | P15884 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015538 | 0.86 | OPRM1 (0.57) | OPRM1OPRD1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20816043 | 0.82 | OPRM1 (0.47) | OPRM1OPRD1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10125216 | 0.78 | POLB (0.45) | MEN1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL20816040 | 0.77 | OPRM1 (0.48) | OPRM1OPRD1MEN1KMT2AL3MBTL1 | |
| SCHEMBL17973534 | 0.75 | CYP2C9 (0.42) | MEN1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL1719650 | 0.75 | IKBKB (0.48) | — | |
| SCHEMBL2184458 | 0.74 | CA1 (0.43) | MEN1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL3360534 | 0.74 | CYP2C9 (0.41) | MEN1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL30877445 | 0.74 | CYP2C9 (0.41) | MEN1KMT2AL3MBTL1POLBKDM4E | |
| SCHEMBL14510748 | 0.73 | OPRM1 (0.34) | OPRM1OPRD1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113347-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-06-10 | — | — | WO | disclosed |