Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015538 | 0.91 | OPRM1 (0.57) | OPRM1OPRD1L3MBTL1LMNAKMT2A | |
| SCHEMBL20816040 | 0.83 | OPRM1 (0.48) | OPRM1OPRD1L3MBTL1LMNAKMT2A | |
| SCHEMBL23484064 | 0.82 | OPRM1 (0.41) | OPRM1OPRD1L3MBTL1LMNAKMT2A | |
| SCHEMBL20816038 | 0.73 | OPRM1 (0.85) | OPRM1OPRD1NPC1RAB9AL3MBTL1 | |
| SCHEMBL20816036 | 0.70 | MET (0.43) | NPC1RAB9ALMNAKMT2AMAPT | |
| SCHEMBL10125216 | 0.70 | POLB (0.45) | L3MBTL1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL6828202 | 0.69 | MAPT (0.46) | OPRM1OPRD1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6828215 | 0.69 | MAPT (0.51) | OPRM1OPRD1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL17973534 | 0.68 | CYP2C9 (0.42) | L3MBTL1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL1719650 | 0.67 | IKBKB (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577371-B2 | Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190084987-A1 | Small Molecule Histone Methyltransferase SUV39H1 Inhibitor and Uses Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577371-B2 | Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof | SUV39H2, SUV39H1, EZH1 | OPRM1 4500/4885OPRD1 4790/4885NPC1 3423/4885 |
| US-20190084987-A1 | Small Molecule Histone Methyltransferase SUV39H1 Inhibitor and Uses Thereof | SUV39H2, SUV39H1, EZH1 | OPRM1 4500/4885OPRD1 4790/4885NPC1 3423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.