Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GALR2 | O43603 | 2/20 | 0.48 |
| ▸ | GALR1 | P47211 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063654 | 0.80 | ULK1 (0.50) | L3MBTL1PDGFRBPDGFRASMN1; SMN2LMNA | |
| SCHEMBL17048156 | 0.79 | KMT2A (0.55) | GALR1PDGFRBPDGFRASMN1; SMN2NPC1 | |
| SCHEMBL4193485 | 0.78 | POLB (0.60) | KMT2AMEN1PDE4APDE4BPDE4C | |
| SCHEMBL17048144 | 0.78 | KMT2A (0.57) | GALR1PDGFRBPDGFRASMN1; SMN2NPC1 | |
| SCHEMBL17048354 | 0.76 | KMT2A (0.51) | PDGFRBPDGFRAKMT2AALDH1A1HPGD | |
| SCHEMBL15934219 | 0.76 | PTPN7 (0.48) | L3MBTL1PDGFRBPDGFRASMN1; SMN2NPC1 | |
| SCHEMBL15934278 | 0.75 | ALDH1A1 (0.49) | L3MBTL1PDGFRBPDGFRASMN1; SMN2NPC1 | |
| SCHEMBL7400686 | 0.74 | APOBEC3G (0.54) | PDGFRBPDGFRASMN1; SMN2TP53TSHR | |
| SCHEMBL17048125 | 0.72 | KMT2A (0.47) | MAPK1RAB9ALMNAKMT2APTGS1 | |
| SCHEMBL4117088 | 0.72 | KMT2A (0.72) | MAPK1SMN1; SMN2NPC1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113795-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC (US) | 2021-06-10 | — | — | WO | disclosed |