Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193485 | 0.81 | POLB (0.60) | MEN1KMT2A | |
| SCHEMBL17048402 | 0.81 | PTGS1 (0.51) | APOBEC3GALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL27589069 | 0.80 | TDP1 (0.61) | APOBEC3GALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8063654 | 0.80 | ULK1 (0.50) | PDGFRBPDGFRAKDM4EMAPTMEN1 | |
| SCHEMBL30352677 | 0.78 | PDE4B (0.48) | — | |
| SCHEMBL15934278 | 0.78 | ALDH1A1 (0.49) | APOBEC3GALDH1A1HPGDPDGFRBPDGFRA | |
| SCHEMBL17048144 | 0.78 | KMT2A (0.57) | ALDH1A1HPGDPDGFRBPDGFRAKDM4E | |
| Cyclopentanone SCHEMBL17048275 | 0.77 | PTGS1 (0.47) | APOBEC3GALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9028851 | 0.76 | ADRA1D (0.55) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17048156 | 0.76 | KMT2A (0.55) | ALDH1A1HPGDPDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064648-A1 | ISOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | disclosed |