Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.70 |
| ▸ | FNTB | P49356 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TGM2 | P21980 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | GALK1 | P51570 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | EP300 | Q09472 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484220 | 0.93 | FNTA (0.82) | FNTAFNTBMAPTKDM4EMEN1 | |
| SCHEMBL30260509 | 0.89 | MAPT (0.87) | FNTAFNTBMAPTKDM4EMEN1 | |
| SCHEMBL25015126 | 0.89 | MAPT (0.87) | FNTAFNTBMAPTKDM4EMEN1 | |
| SCHEMBL20250622 | 0.87 | FNTA (0.65) | FNTAFNTBMAPTKDM4EMEN1 | |
| SCHEMBL20257205 | 0.85 | SMN1; SMN2 (0.75) | FNTAFNTBMAPTKDM4EMEN1 | |
| Streptonigrin SCHEMBL29371276 | 0.82 | MAPT (1.00) | FNTAFNTBMAPTKDM4EMEN1 | |
| Streptonigrin SCHEMBL29821157 | 0.82 | MAPT (1.00) | FNTAFNTBMAPTKDM4EMEN1 | |
| Streptonigrin SCHEMBL29374011 | 0.82 | MAPT (1.00) | FNTAFNTBMAPTKDM4EMEN1 | |
| Streptonigrin SCHEMBL23421492 | 0.75 | LMNA (0.85) | FNTAFNTBMAPTKDM4EMEN1 | |
| Streptonigrin SCHEMBL6299739 | 0.75 | LMNA (0.84) | FNTAFNTBMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113347-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-06-10 | — | — | WO | disclosed |