Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481174 | 0.83 | HRH3 (0.43) | GPR119USP2SMN1; SMN2HRH3DDB1 | |
| SCHEMBL24993819 | 0.83 | NR1H2 (0.36) | NR1H2HRH3 | |
| SCHEMBL23484250 | 0.78 | GPR119 (0.35) | NR1H2GPR119USP2SMN1; SMN2HRH3 | |
| SCHEMBL23459192 | 0.77 | HRH3 (0.36) | GPR119USP2SMN1; SMN2HRH3DDB1 | |
| SCHEMBL23459191 | 0.77 | HRH3 (0.36) | GPR119USP2SMN1; SMN2HRH3DDB1 | |
| SCHEMBL23459309 | 0.77 | HRH3 (0.36) | GPR119USP2SMN1; SMN2HRH3DDB1 | |
| SCHEMBL3035597 | 0.76 | USP2 (0.45) | GPR119USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL7840359 | 0.76 | USP2 (0.45) | GPR119USP2SMN1; SMN2HRH3DDB1 | |
| SCHEMBL23460060 | 0.75 | HSD11B1 (0.31) | — | |
| SCHEMBL23481314 | 0.74 | USP2 (0.37) | NR1H2GPR119USP2SMN1; SMN2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073075-A1 | SSTR5 ANTAGONISTS | Kallyope, Inc. (US) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021113362-A1 | SSTR5 ANTAGONISTS | KALLYOPE, INC. (US) | 2021-06-10 | — | — | WO | disclosed |