Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24994873 | 0.92 | POLB (0.37) | POLBRAD52TERTVCAM1GAA | |
| SCHEMBL23486017 | 0.88 | POLB (0.39) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL23485984 | 0.82 | POLB (0.35) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL23485752 | 0.81 | POLB (0.36) | POLBRAD52TERTNPC1SLC2A1 | |
| SCHEMBL24994173 | 0.79 | POLB (0.40) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL23485986 | 0.76 | MERTK (0.39) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL24994174 | 0.73 | TERT (0.33) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL23485853 | 0.69 | ADAM17 (0.32) | KMT2A | |
| SCHEMBL23458203 | 0.67 | POLB (0.47) | POLBRAD52TERTGAAKDM4E | |
| SCHEMBL29862950 | 0.67 | POLB (0.47) | POLBRAD52TERTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110280-A1 | AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2021-06-10 | — | — | WO | disclosed |