Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486350 | 1.00 | KLKB1 (0.43) | KLKB1PLGPLAUMMP1MAPT | |
| SCHEMBL23486351 | 0.90 | KLKB1 (0.47) | KLKB1PLGPLAUMMP1MEN1 | |
| SCHEMBL23486820 | 0.88 | MMP1 (0.42) | KLKB1PLGPLAUMMP1MAPT | |
| SCHEMBL23486821 | 0.88 | MMP1 (0.42) | KLKB1PLGPLAUMMP1MAPT | |
| SCHEMBL23486474 | 0.88 | MAPT (0.41) | KLKB1MMP1MAPTNPSR1MEN1 | |
| SCHEMBL29139690 | 0.86 | S1PR1 (0.40) | KLKB1MMP1MAPTNPSR1MEN1 | |
| SCHEMBL23486357 | 0.86 | FPR2 (0.42) | KLKB1MMP1MAPTNPSR1MEN1 | |
| SCHEMBL23486780 | 0.84 | MMP1 (0.40) | KLKB1PLGPLAUMMP1MAPT | |
| SCHEMBL23486652 | 0.84 | KLKB1 (0.40) | KLKB1PLGPLAUMMP1MAPT | |
| SCHEMBL23466781 | 0.83 | CHRM2 (0.41) | KLKB1PLGPLAUMMP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |