Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 10/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486348 | 0.90 | KLKB1 (0.43) | KLKB1PLGPLAUF11PRSS1 | |
| SCHEMBL23486350 | 0.90 | KLKB1 (0.43) | KLKB1PLGPLAUF11PRSS1 | |
| SCHEMBL30680264 | 0.87 | NPC1 (0.42) | MEN1KMT2A | |
| SCHEMBL28974403 | 0.87 | MMP1 (0.44) | KLKB1PLGPLAUF11PRSS1 | |
| SCHEMBL30680273 | 0.87 | MMP1 (0.44) | KLKB1PLGPLAUF11PRSS1 | |
| SCHEMBL23486816 | 0.87 | MMP1 (0.44) | KLKB1PLGPLAUF11PRSS1 | |
| SCHEMBL29758157 | 0.86 | F11 (0.45) | KLKB1F11S1PR1KLK1 | |
| SCHEMBL23466522 | 0.86 | F11 (0.45) | KLKB1F11S1PR1KLK1 | |
| SCHEMBL23466521 | 0.86 | F11 (0.45) | KLKB1F11S1PR1KLK1 | |
| SCHEMBL29139606 | 0.85 | S1PR1 (0.44) | KLKB1F11S1PR1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |