Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158442 | 0.78 | TSHR (0.65) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL23486737 | 0.77 | CHRNB2 (0.42) | TSHRHPGDALDH1A1 | |
| SCHEMBL20405434 | 0.75 | ALDH1A1 (0.61) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL11184712 | 0.73 | ALDH1A1 (0.72) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL2952745 | 0.72 | TSHR (0.57) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL3087285 | 0.72 | TSHR (0.57) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL3087287 | 0.72 | TSHR (0.57) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL13194529 | 0.72 | TSHR (0.57) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL2952742 | 0.72 | TSHR (0.57) | TSHRSMN1; SMN2POLBHPGDRECQL | |
| SCHEMBL2077746 | 0.70 | TSHR (0.65) | TSHRSMN1; SMN2POLBHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |