Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486400 | 0.77 | TSHR (0.49) | ALDH1A1TSHRHPGD | |
| SCHEMBL24706079 | 0.77 | CHRNB2 (0.58) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL19271816 | 0.71 | HSD11B1 (0.69) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL18637326 | 0.70 | — | — | |
| SCHEMBL24890582 | 0.70 | — | — | |
| SCHEMBL19188063 | 0.68 | CHRNB2 (0.55) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL23288610 | 0.66 | TP53 (0.41) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL23486494 | 0.66 | DPP4 (0.37) | — | |
| SCHEMBL18533756 | 0.64 | — | — | |
| SCHEMBL24341885 | 0.63 | HPGD (0.52) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |