Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.64 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914364 | 0.82 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5914363 | 0.82 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5744716 | 0.82 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5744720 | 0.82 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7359263 | 0.78 | SLC15A1 (1.00) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7359267 | 0.78 | SLC15A1 (1.00) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5647916 | 0.76 | EPHX1 (0.52) | SLC15A1ALPIPKMPTGS1XIAP | |
| Amphetamine SCHEMBL20839574 | 0.75 | TAAR1 (0.70) | SLC15A1ALPIPKMPTGS1XIAP | |
| Amphetamine SCHEMBL28463265 | 0.75 | TAAR1 (0.70) | SLC15A1ALPIPKMPTGS1XIAP | |
| Amphetamine SCHEMBL28824543 | 0.75 | TAAR1 (0.70) | SLC15A1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358663-A1 | ENANTIOSELECTIVE SYNTHESIS OF -AMINO- , -UNSATURATED CARBOXYLIC ACID DERIVATIVES | Novartis AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010055162-A1 | ENANTIOSELECTIVE SYNTHESIS OF γ-AMINO-α,β-UNSATURATED CARBOXYLIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | disclosed |