SCHEMBL7359267

SCHEMBL7359267

NC(Cc1ccccc1)C(O)C=CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 2/20 1.00
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
PTGS1 P23219 1/20 0.49
XIAP P98170 1/20 0.49
SLC7A5 Q01650 1/20 0.49
LAP3 P28838 7/20 0.47
ANPEP P15144 2/20 0.47
RNPEP Q9H4A4 1/20 0.47
DNPEP Q9ULA0 1/20 0.47
TAAR1 Q96RJ0 1/20 0.45
SLC1A3 P43003 2/20 0.45
SLC1A2 P43004 2/20 0.45
SLC1A1 P43005 2/20 0.45
CTSL P07711 1/20 0.44
CYP1A2 P05177 1/20 0.43
LTA4H P09960 1/20 0.43
EPHX1 P07099 1/20 0.42
CSNK1E P49674 1/20 0.42
SRR Q9GZT4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7359263 1.00 SLC15A1 (1.00) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL5914363 0.81 SLC15A1 (0.68) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL5744720 0.81 SLC15A1 (0.68) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL5914364 0.81 SLC15A1 (0.68) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL5744716 0.81 SLC15A1 (0.68) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL6243844 0.79 SLC15A1 (0.65) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL11025293 0.79 SLC15A1 (0.65) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL6580784 0.79 SLC15A1 (0.65) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL2348641 0.78 SLC15A1 (0.64) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL7268674 0.78 LAP3 (0.65) SLC15A1PKMLAP3ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415981-A4 RETROVIRAL PROTEASE INHIBITORS 1991-10-09 EP disclosed
EP-0415981-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1991-03-13 EP disclosed
EP-0342541-A2 Retroviral protease inhibitors ABBOTT LABORATORIES (US) 1989-11-23 EP disclosed
WO-1989010752-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1989-11-16 WO disclosed