Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.68 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914364 | 1.00 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5744720 | 1.00 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5914363 | 1.00 | SLC15A1 (0.68) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL15756473 | 0.88 | SLC15A1 (0.58) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL15756471 | 0.88 | SLC15A1 (0.58) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5814047 | 0.87 | SLC15A1 (0.53) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL2348641 | 0.82 | SLC15A1 (0.64) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7416137 | 0.82 | SLC15A1 (0.55) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7416145 | 0.82 | SLC15A1 (0.55) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7416141 | 0.82 | SLC15A1 (0.55) | SLC15A1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223814-A1 | Nk-2 antagonist basic linear compounds and formulations containing them | MENARINI RICERCHE S.P.A. (IT) | 2006-10-05 | — | — | US | disclosed |
| EP-1620432-A1 | NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004094412-A1 | NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223814-A1 | Nk-2 antagonist basic linear compounds and formulations containing them | BDKRB2, KLK2, BDKRB1 | SLC15A1 1201/4885ALPI 3046/4885PKM 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.