Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363484 | 0.87 | USP2 (0.56) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL23490200 | 0.85 | TNF (0.54) | USP2SMN1; SMN2L3MBTL1MAPTKMT2A | |
| SCHEMBL23486901 | 0.78 | USP2 (0.56) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL23486903 | 0.78 | ALDH1A1 (0.49) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL23486912 | 0.76 | L3MBTL1 (0.67) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL31628003 | 0.72 | SMN1; SMN2 (0.55) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL25489137 | 0.72 | TNF (0.56) | USP2SMN1; SMN2L3MBTL1MAPTKMT2A | |
| SCHEMBL23486911 | 0.72 | KMT2A (0.55) | USP2SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL3770638 | 0.71 | USP2 (0.57) | USP2SMN1; SMN2L3MBTL1MAPTKMT2A | |
| SCHEMBL15504850 | 0.71 | L3MBTL1 (0.64) | USP2SMN1; SMN2L3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113690-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |