Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543420 | 0.86 | CYP2A6 (0.61) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL472043 | 0.86 | CYP2A6 (0.61) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL472037 | 0.84 | CYP2A6 (0.58) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12819222 | 0.80 | CYP2A6 (0.65) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30025900 | 0.80 | CYP2A6 (0.65) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30026143 | 0.80 | CYP2A6 (0.70) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20541087 | 0.80 | CYP2A6 (0.70) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21110859 | 0.78 | CYP2A6 (0.67) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12853987 | 0.78 | CYP2A6 (0.67) | CYP11B1CYP2A6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23487550 | 0.78 | CYP2A6 (0.41) | CYP11B1CYP2A6CYP3A4PTGS2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2021110720-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | CYP11B1 1353/4885CYP2A6 4118/4885ALDH1A1 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.