Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354976 | 0.82 | SLC1A1 (0.49) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL15671106 | 0.79 | TSHR (0.39) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7371632 | 0.78 | TSHR (0.37) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL3393137 | 0.77 | TSHR (0.43) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL24529183 | 0.77 | ALDH1A1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL4957134 | 0.76 | — | — | |
| SCHEMBL2217142 | 0.76 | TSHR (0.57) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL1261022 | 0.76 | LMNA (0.44) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL28225417 | 0.74 | TSHR (0.44) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL18116498 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289839-A1 | NOVEL AURORA KINASE INHIBITOR AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2021110009-A1 | NOVEL AURORA KINASE INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2021-06-10 | — | — | WO | disclosed |