Tetrapropylammonium

Tetrapropylammonium

SCHEMBL2348766

CCC[N+](CCC)(CCC)CCC.O=C([O-])/C=C\C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol

The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 1/20 0.42
HCAR2 Q8TDS4 5/20 0.40
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
BBOX1 O75936 1/20 0.38
PLA2G1B P04054 2/20 0.34
ATG4B Q9Y4P1 2/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrapropylammonium SCHEMBL28970865 1.00 SLC22A1 (0.42) SLC22A1HCAR2TSHRTP53EGLN1
Tetrapropylammonium SCHEMBL106231 1.00 SLC22A1 (0.42) SLC22A1HCAR2TSHRTP53EGLN1
Tetrapropylammonium SCHEMBL2350618 1.00 SLC22A1 (0.42) SLC22A1HCAR2TSHRTP53EGLN1
Fumaric Acid SCHEMBL4948614 0.92 HCAR2 (0.37) SLC22A1HCAR2TSHRTP53EGLN1
Fumaric Acid SCHEMBL4921160 0.92 HCAR2 (0.37) SLC22A1HCAR2TSHRTP53EGLN1
Fumaric Acid SCHEMBL4928055 0.92 HCAR2 (0.37) SLC22A1HCAR2TSHRTP53EGLN1
Tetrapropylammonium SCHEMBL105473 0.91 SLC22A1 (0.50) SLC22A1BBOX1
Tetrapropylammonium SCHEMBL107831 0.91 SLC22A1 (0.50) SLC22A1BBOX1
Tetrapropylammonium SCHEMBL106232 0.91 SLC22A1 (0.50) SLC22A1BBOX1
Tetrapropylammonium SCHEMBL2347035 0.89 SLC22A1 (0.48) SLC22A1BBOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP claimed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN claimed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US claimed
US-9878318-B2 Trimer catalyst additives for improving foam processability EVONIK DEGUSSA GMBH (DE) 2018-01-30 US claimed
US-20180009930-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2018-01-11 US claimed
US-9815932-B2 Trimer catalysts with improved processability and surface cure EVONIK DEGUSSA GMBH (DE) 2017-11-14 US claimed
EP-3144332-A1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-03-22 EP claimed
US-20140042361-A1 TRIMER CATALYSTS WITH IMPROVED PROCESSABILITY AND SURFACE CURE EVONIK OPERATIONS GMBH (DE) 2014-02-13 US claimed
US-20140005037-A1 TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2014-01-02 US claimed
US-20080312351-A1 Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-12-18 US claimed
EP-2003157-A2 Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications Air Products and Chemicals, Inc. (US) 2008-12-17 EP claimed
US-20070259982-A1 Trimer catalysts with improved processability and surface cure EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP disclosed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN disclosed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-0227433-B1 ELECTROLYTE SOLUTION OF QUATERNARY AMMONIUM SALT FOR ELECTROLYTIC CAPACITOR MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-01-15 EP disclosed
US-4715976-A QUATERNARY AMMONIUM SALT OF CARBOXYLIC ACID IN APROTIC SOLVENT MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-12-29 US disclosed