Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622774 | 1.00 | GAA (0.51) | GAAMEN1KMT2ADRD2DRD3 | |
| SCHEMBL10744283 | 0.88 | POLB (0.46) | GAADRD2DRD3HTR2BKCNH2 | |
| SCHEMBL8544664 | 0.86 | MAPK1 (0.56) | GAADRD2DRD3HTR2BKCNH2 | |
| SCHEMBL21054952 | 0.85 | GAA (0.56) | GAAMEN1KMT2ADRD2DRD3 | |
| SCHEMBL10744279 | 0.84 | GAA (0.51) | GAAMEN1KMT2ADRD2DRD3 | |
| SCHEMBL27631394 | 0.84 | GAA (0.55) | GAAMEN1KMT2ADRD2DRD3 | |
| SCHEMBL10723820 | 0.84 | DRD2 (0.50) | GAADRD2DRD3HTR2BKCNH2 | |
| SCHEMBL31038303 | 0.84 | CA2 (0.52) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL30219287 | 0.84 | SMN1; SMN2 (0.57) | GAAMEN1KMT2ADRD2DRD3 | |
| SCHEMBL29598834 | 0.84 | GAA (0.65) | GAAMEN1KMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| CN-117074579-B | Analysis method of related substances of amisulpride oral solution | 江苏东科康德药业有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117074579-A | Analysis method of related substances of amisulpride oral solution | 江苏东科康德药业有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116836093-A | 4-amino-5-alkylsulfinyl-2-methoxybenzoic acid compound and preparation method and application thereof | 江苏恩华药业股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-114401717-A | Modified release formulations and uses thereof | 赛诺维信制药公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-112236138-A | Crystalline forms and methods of making the same | 赛诺维信制药公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-112118838-A | Non-racemic mixtures and uses thereof | 赛诺维信制药公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-3720435-A1 | CRYSTAL FORMS AND PRODUCTION METHODS THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019113084-A1 | CRYSTAL FORMS AND PRODUCTION METHODS THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2019-06-13 | — | — | WO | disclosed |
| WO-2011103448-A1 | METHODS AND COMPOSITIONS FOR TREATING PSYCHOTIC DISORDERS USING ANTIPSYCHOTIC COMBINATION THERAPY | MEDIVATION TECHNOLOGIES, INC. (US) | 2011-08-25 | — | — | WO | disclosed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |
| CN-1252720-A | Gastric-retained pharmaceutical compositions | SANOFI SYNTHELABO (FR) | 2000-05-10 | — | — | CN | disclosed |
| EP-0037990-A1 | Phenyl quinolizidines, corresponding pharmaceutical preparations, the preparation of the active compounds and corresponding starting compounds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-21 | — | — | EP | disclosed |
| US-3975434-A | Processes of producing 2,5-disubstituted benzamides | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-08-17 | — | — | US | disclosed |